9 Top Business Hotels in San Francisco (2026)

Set on a narrow peninsula between the Pacific Ocean and San Francisco Bay, San Francisco is a compact, fast moving city known for its steep streets, downtown, and distinct neighbourhoods. Most of the business hotels here are geared towards travellers who want things to run smoothly, whether that means staying close to the Financial District, near Moscone Centre, or by the Embarcadero. You’ll find everything from corporate favourites with great meeting facilities to smarter boutique hotels and more affordable options. These are places that make work trips easier, with comfortable rooms and great locations.

For city chic

• Near Union Square, Hotel Zetta balances character with practicality. Rooms feature reclaimed wood and vintage details, while the business centre and meeting room are ideal for presentations. There is strong Wi-Fi throughout, and the lively bar and British brasserie double as informal meeting spots after office hours.
• Between Union Square and the Financial District, Galleria Park is set up for chic business stays. Meeting rooms and a business centre cover the basics, the Wi-Fi is solid, and the French brasserie is handy for quick catch-ups. The rooftop garden is a bonus when you need a break from screens. 
• Just off Union Square, Taj Campton Place suits more formal business travel. Rooms are quiet and well insulated for work, while the Michelin-starred restaurant works well for client dinners. Private meeting rooms, a full business centre, and a 24/7 rooftop gym make for a practical, well-located and comfortable stay.

For pure luxury

• Just off Union Square, Hotel Spero nails luxury city living for work trips. Rooms feel warm and comfortable, with soft lighting, plush fabrics, and graphic details. Jasper’s Kitchen downstairs is a big plus, while meeting rooms, a business centre, and strong Wi-Fi keep things running smoothly.
• Up on Nob Hill, the Ritz Carlton San Francisco is a grand five-star base that feels calm and well set up for work trips. There’s a full business centre, well-run meeting rooms, and a Michelin-led restaurant that works perfectly for client dinners. Rooms are spacious and pared back, with marble bathrooms and proper desks.
• 1 Hotel San Francisco is situated right on the Embarcadero, and is ideal if you like space and light. Rooms look out over the water and feel refined. Work needs are covered with meeting rooms and a business centre, while the rooftop garden, spa, and restaurant offer downtime after a busy day.

For a historic stay

• Right at the top of Nob Hill, the Intercontinental Mark Hopkins is a long-standing San Francisco favourite that leans into its history. Rooms feel classic and calm, with neutral tones, big windows, and space to work. The real draw is the 19th-floor bar for post-meeting drinks, plus solid meeting rooms and a reliable business centre.
• The Palace Hotel, San Francisco, is all about old-school grandeur. High ceilings, marble bathrooms, and grand public spaces set the tone here. The glass-domed Garden Court is made for client meetings, while conference facilities, a business centre, and a central location make it ideal for working guests.

For a boutique hotel

• Right in the middle of Japantown, Hotel Kabuki feels closely tied to its surroundings. Rooms use Asian inspired touches like graphic prints and wooden screens, creating a calm, focused space that suits business stays. Nari’s Thai restaurant and the Japanese whisky bar make after-hours meetings easy.

Still not sure?

• Expand your search to see all our recommendations in San Francisco,
• Browse through our lists of the best San Francisco hotels with a pool, the best family hotels in San Francisco or the best pet friendly hotels in San Francisco, 
• Or, contact one of our friendly Gurus for personalised advice.