The 8 Best Hotels in Santa Cruz, Seville (2025)

Santa Cruz is the true centre of Seville. Draw a ring around the incredible Gothic cathedral and you’ll find it filled with winding, cobbled alleys, small squares with flowery balconies and traditional cafes, restaurants and tapas bars. If you choose to stay in one of the best hotels in Santa Cruz you’ll be right in the heart of things. It is bordered by the Real Alcázar, the Calle Mateos Gago, the Calle Santa María La Blanca, and the Jardines de Murillo - some of Seville’s headline sights. The Giralda, which was once a minaret, also belongs on this ‘must-do’ list. 

Santa Cruz was the old Jewish quarter and its labyrinth of streets were designed to protect the inhabitants from the sun of a Sevillian summer. If you’re interested in this part of the area’s history make sure to visit the covered passageways of the Juderia. As well as being central, historic, extremely atmospheric, beautiful and smelling heavenly - there are a lot of orange trees here.

For your stay in this stunning part of Seville, our experts have come up with a curated collection of the best hotels in Santa Cruz. Whether you're looking for elegance and character, great value, or fantastic views in a central spot, there's something for everyone.

For luxury

 

• Casa 1800 is a luxurious hotel with 33 rooms arranged around an elegant central courtyard. The decor is perfect - think opulent chandeliers, exposed stone and four-poster beds. You are in the vibrant heart of town with a rooftop terrace and pool offering spectacular views.
• With opulent suites, stately grounds and a romantic restaurant, Hotel Alfonso XIII is perfect for an indulgent getaway. Located in a custom-designed hotel commissioned by Spanish royalty with a blend of Moorish and European influences, this hotel oozes elegant Sevillan charm.

For the location

• The EME Catedral Hotel is a sumptuous hotel with an amazing roof terrace with views of the cathedral. The decor is stylish and there’s a Michelin-starred restaurant and a luxurious spa.
• Smaller and simpler, the U-Sense Sevilla Centro hotel is across the quiet, pedestrianised way from the cathedral - we’re talking just 50 metres. Not surprisingly that means the cathedral views from the bedroom’s balconies are a touch detailed, but it’s pretty amazing. The decor is minimalist and the rooms are large and well laid out.

For great value

• The Hotel Elvira Plaza is a charming, boutique hotel with nine, chic, whitewashed rooms with large windows opening out onto the street of a very central, but tree-lined plaza. There are two restaurants, and rooms start at very reasonable rates.
• Also with an appealing price tag is Hotel Dona Maria, a well located townhouse hotel with 62 traditionally elegant rooms and suites - some suitable for families, just a five-minute walk from the Alcázar of Seville. The hotel has an elegant sitting room, an exotic courtyard, and a rooftop pool with cathedral views.
• The Corner House is a beautifully renovated property in the heart of this historic centre. The 12 reasonably-priced rooms feature white-washed walls set against vibrant patterns and simple minimalist furniture. There's also a rooftop bar serving cocktails with a view.

For a unique stay

• The Hotel Amadeus & La Musica is a 30-room, family-owned hotel with a musical theme. Beyond the regular music recitals and decor with a musical bent, there’s a roof terrace with panoramic views, whitewashed walls, wooden shutters and Moorish furnishings.

If you haven’t found your idea of the best hotels in Santa Cruz on our Gurus' list of the 8 Best Hotels in Santa Cruz, you could:

• Browse through our list of all the best places to stay in Seville
• Or consider our Gurus' recommendations for the best Seville hotels with pools, 4 Best Hotels in Centro Seville or one of the 5 Best Hotels in Alfalfa
• Or you might want to contact one of our friendly Gurus for personalised advice.

The 8 Best Hotels in Santa Cruz