Best Central Hotels in St Louis (2025)

St. Louis sits at the meeting point of the Mississippi and Missouri Rivers; it's a city alive with soaring archways, leafy parks, and neighbourhoods that each tell their own story. Its streets buzz with music, sports, and a rich cultural history that invites exploration. Right in the heart of it all, St Louis' best central hotels put you steps from iconic attractions and trendy dining scenes. From sleek high-rises with rooftop pools to historic gems steeped in Art Deco charm, there’s a property here to suit every taste and budget.

For city chic

• Live! by Loews St Louis sits opposite Busch Stadium and boasts modern rooms featuring subtle baseball-inspired touches. Rooftop drinks, a sleek steakhouse, and Bar Bourbon complete the picture, and families benefit from free stays for kids under 18. Perfect for city explorers, game-day visitors, or anyone craving chic, contemporary style.

For luxury

• Four Seasons St Louis is an iconic city retreat with plush interiors and floor-to-ceiling windows for epic city views. The rooftop terrace buzzes with firepits, cabanas, and a lively bar alongside a pool. Its understated elegance, romantic spa experiences, and thoughtful family amenities make it perfect for both intimate escapes and city adventures.

For a historic building

• Hotel Saint Louis is a historic St Louis landmark property, where 19th-century architecture meets Art Deco interiors. Palatial rooms, a rooftop pool with sweeping city views, and a spa offering massages and beauty treatments create a spoiling urban retreat. Stylish dining and art-filled meeting spaces ensure it's ideal for business or leisure.

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